Now theoretically you could connect a plastic guitar to some synthesizer and then connect its output to Rocksmith USB Cable (the only device that RS officially recognizes, and it requires Analog input). You can check out their official website and ask their support if you wish. I play RS for over a year, and this is the first time ever I heard idea like yours. The whole sale pitch of this product is ability to recognize your real instrument. There's no support for plastic controllers ever declared for this or previous versions of the game. You pretty much can take our word on this issue. They might have referred to the fact that this game features dynamic difficulty, and (on some songs) at lowest difficulty you only have to work with 2 fingers on same string, without changing hand position. I can't find the trailer I watched for a direct quote, but it definitely said something along the lines of 'the easier mode is like one of the games with the plastic guitar', obviously referring to Guitar Hero and Rock Band. Other than that, this is nothing like Guitar Hero. * You have to keep rhythm to hit the notes Originally posted by Rogue203:No, you can't do that.